PGT is a sophisticated screening method used in conjunction with in vitro fertilization (IVF). It analyzes embryos for potential genetic or chromosomal variations before they are transferred to the uterus. This process helps identify genetic disorders or chromosomal problems, allowing for the selection of embryos with the highest likelihood of resulting in a healthy pregnancy. PGT can be a valuable tool for couples seeking to improve their IVF success rates.
While PGT is not a standard part of every IVF cycle, it is often recommended for couples who have certain risk factors. The aim of PGT is to minimize the risk of miscarriage, unsuccessful IVF cycles, and the transmission of genetic conditions to offspring. Fertility specialists may suggest PGT in the following circumstances:
Family History of Genetic Disorders: Couples with a family history of inherited genetic conditions may be at increased risk of passing these genes to their children. PGT can screen embryos for these specific genetic variations, enabling the selection of unaffected embryos for transfer.
Recurrent Pregnancy Loss: Couples experiencing repeated miscarriages, possibly due to chromosomal abnormalities in the embryos, may benefit from PGT. This testing can help identify embryos with chromosomal issues that could increase the risk of future pregnancy loss.
Parental Age: As individuals age, particularly women over 35, there is a greater chance of genetic variations and chromosomal abnormalities in the embryos. PGT can assist in selecting chromosomally typical embryos, potentially increasing the likelihood of a successful pregnancy.
Known Genetic Conditions: Couples who are carriers for or concerned about passing on specific genetic conditions may use PGT to screen embryos and select those that are not affected by the condition.
By identifying and selecting embryos without these variations, PGT can improve the chances of a healthy pregnancy and provide reassurance to couples undergoing IVF.